🧬 Dinkov DistilledOutline

NADplus-NADH Ratio

Published: 6/23/2025

NAD+/NADH Ratio

As we have established, the NADâș/NADH ratio is the ultimate arbiter of your cellular fate. It is the true north on your metabolic compass, the master switch that dictates whether your cells are in a state of efficient energy production or congested, reductive stress.

To recap its critical importance:

  • A High NADâș/NADH Ratio is the hallmark of the oxidized state. It is the "go" signal for efficient glucose oxidation, forward electron flow, and robust CO₂ production. A higher ratio is beneficial, indicating that the cellular power grid is running smoothly.

  • A Low NADâș/NADH Ratio is the signature of the reduced state. It is the "stop" signal of a backed-up system, forcing the cell towards lactate fermentation, fat synthesis, and the production of inflammatory byproducts.